Lewis-Francis failed to make it through the heats in Oslo recently

Lewis-Francis is out with a hamstring injury while Campbell and Gardener both have ongoing back problems.

Craig Pickering, Harry Aikines Aryeetey and Dwayne Grant will take their places in the 4x100m relay team in Malaga.

Emma Ania has withdrawn from the women's relay team because of illness with Anyika Onuora taking her place.

"All the athletes are obviously very disappointed but have acted professionally in not travelling whilst carrying injury or illness," said UK Athletics senior performance manager for speed John Trower.

"In selecting replacements in the men's squad we have three very strong performers - Craig was part of the Helsinki relay squad, Dwayne played a part in the Athens squad and Harry is well established in the relay programme.

"Anyika is the natural replacement for Emma who has sadly been taken ill, but has done the right thing in pulling out."

Revised Great Britain and Northern Ireland team for European Cup in Malaga, 28-29 June:
Men:
100m: Dwain Chambers
200m: Christian Malcolm
400m: Graham Hedman
800m: Richard Hill
1500m: Andrew Baddeley
3000m: Mo Farah
5000m: Chris Thompson
110m hurdles: Andy Turner
400m hurdles: Rhys Williams
3000m steeplechase: Adam Bowden
High jump: Germaine Mason
Pole Vault: Steve Lewis
Long jump: Greg Rutherford
Triple jump: Nathan Douglas
Shot: Carl Myerscough
Discus: Carl Myerscough
Hammer: Andy Frost
Javelin: Nick Nieland
4x100m relay: Christian Malcolm, Tim Abeyie, Craig Pickering, Dwain Chambers, Marlon Devonish, Harry Aikines Aryeetey, Dwayne Grant
4x400m relay: Richard Buck, Malachi Davis, Graham Hedman, Andrew Steele, Richard Strachan, Robert Tobin
Travelling reserves: Dale Garland, Mark Warmby

Women:
100m: Joice Maduaka
200m: Abi Oyepitan
400m: Nicola Sanders
800m: Rebecca Lyne
1500m: Lisa Dobriskey
3000m: Jo Pavey
5000m: Kathy Butler
100m hurdles: Sarah Claxton
400m hurdles: Natasha Danvers-Smith
3000m steeplechase: Elizabeth Hall
High jump: Julie Crane
Pole vault: Kate Dennison
Long jump: Kelly Sotherton
Triple jump: Nadia Williams
Shot: Joanne Duncan
Discus: Philippa Roles
Hammer: Zoe Derham
Javelin: Goldie Sayers
4x100m relay: Anyika Onuora, Emily Freeman, Jeanette Kwayke, Joice Maduaka, Abi Oyepitan, Laura Turner
4x400m: Emma Duck, Helen Karagounis, Lee McConnell, Jenny Meadows, Melanie Purkiss, Nicola Sanders, Natasha Danvers-Smith
Travelling reserve: Tina Brown