And if you wash your hair every day it'll be glossy just like mine

Clever mix of real life and animation in which the body is depicted as a city, with veins as motorways and a mayor in charge of the brain.

Nigel Bell

Frank (Murray) is an out of condition zoo keeper who suddenly runs into trouble when he eats a hard boiled egg which has been sucked by a chimpanzee and allowed to roll around in some dirty straw.

A deadly virus enters his system, at which point the film switches from real life to animation and really comes alive.

Give me 24 hours and I'll clean up this city...err...body

Our hero, Osmosis Jones (Rock), is a white blood cell. Inside the "City of Frank" white blood cells act as police officers.

Jones teams up with a cold pill called Drix (excellently voiced by Frasier star Hyde Pierce) to take on the evil virus Thrax (Fishburne) who's out to beat his all time record for killing a human. He aims to finish off Frank in 48 hours.

What you are left with is a cartoon, buddy cum race against time movie. Quite a combination.

Some vivid imagination has gone into this. The stomach is visualised as an airport complete with Hare Krishna cells, the bladder is a ferry service while the Mafia run the arm pit!

There's even a news service - NNN (Nerve Network News) - to keep different parts of the body up to date with what's happening.

Who you gonna call?

Despite all this Osmosis Jones could well run into problems in terms of audience. It could struggle to find its niche.

It's humour will go over the heads of many youngsters who might be attracted by the animation. It tries to be hip but will teens be convinced by a cartoon and live action Bill Murray?

The fact that the Farrelly brothers (of Me, Myself and Irene fame) are on board could attract a crowd. However, the live action they're in charge of isn't a patch on the animation.

As Harry Potter beckons, Osmosis Jones could well become a victim of He Who Cannot Be Named. That would be a shame. There are some great one liners in this film such as the two cops talking about what they're going to do at the weekend.

"Me and my girlfriend are going down to the kidneys to see the Stones."