Police are preparing for a major operation ahead of Saturday's Championship football match between Stoke City and Birmingham City. Disturbances broke out when the clubs last met at the Britannia Stadium during an FA Cup tie in February, when 39 people were arrested.
An expected full house combined with roadworks and Saturday shopping traffic are likely to cause serious congestion.
Fans are urged to try to avoid taking their cars.
Stoke supporters are urged to use the shuttle bus from Glebe Street to get to the ground, while Birmingham fans are asked to use organised coaches direct to the venue, where there are also roadworks nearby.
Traffic heading for the Britannia from the A500 will have to continue to the exit near the large Tesco on Bath Road, which suffers from regular Saturday congestion without extra football traffic.
Supt Mick Harrison said: "We're expecting a large home and away following at the stadium this weekend, and it is vital that anyone intending to watch the match remembers that the slip road off the A50 towards Blurton is now closed while a new access road is being built."