Muslims around the world, like this family in Calcutta, India, listened intently as President Obama outlined his hopes for a new dialogue between the US and the Islamic world.
These militants in Gaza City heard President Obama say that Palestinians must abandon violence and that resistance through killing and violence is wrong.
In a barbers shop in Jerusalem, customers heard Mr Obama say that the situation for the Palestinians was "intolerable".
There was a cautious reaction from Israel, hoping for a new era of reconciliation but insisting on security.
President Obama's quotes from the Koran, such as "Be conscious of God and speak always the truth", brought cheers in Mogadishu, Somalia.
In Kashmir, this family heard the president say that extremists in Afghanistan and Pakistan posed a threat to Americans.
The reaction in Egypt, where President Obama chose to make his speech, was cautiously optimistic.
In Saudi Arabia, one political analyst said Mr Obama's speech would be well received in the Arab world but added: "Whether it will be successful in bridging the gap, that will take time."
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