McAdams with co-best kiss winner Ryan Gosling

She picked up best breakthrough female performance for Mean Girls, best kiss for The Notebook and a third award with the whole cast of Mean Girls.

Indie hit Napoleon Dynamite picked up best film, Leonardo DiCaprio was best male and Lindsay Lohan was best female.

The awards, voted for by viewers, also reunited the cast of 1980s teen hit The Breakfast Club.

The cast of the film, including Molly Ringwald, Ally Sheedy and Anthony Michael Hall, was serenaded onto the stage by rock band Yellowcard.

Cruise is escorted on stage by girlfriend Katie Homes

The cable network also gave its first lifetime achievement award to Tom Cruise, who accepted it from girlfriend Katie Holmes.

"If I've been able to entertain you at all, okay? Then, I thank you for allowing me to do so," Cruise said.

Child actress Dakota Fanning, who stars with Cruise in the forthcoming War of the Worlds, won best frightened performance for Hide and Seek, and Dustin Hoffman got comedic performance for Meet the Fockers.