Wisconsin declared a state of emergency after being hit by up to 48cm (19in) of snow on Wednesday, while Iowa recorded its worst snowfall for 20 years.
Searchers headed out again on Thursday in northern Arizona to look for elk hunters trapped when up to 3ft of snow fell on Monday and Tuesday.
A local sheriff's spokesman told the Associated Press news agency the priority was to find them before the next storm hits, possibly at the weekend.
Rescuers are looking for 16 people in five parties. Some 50 people have already been rescued.
"The storm just hit when everybody was out in the field," sheriff's spokesman Gerry Blair told AP.
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