Infant mortality is also a serious problem - in poorer countries such as Mali, more than 10% of babies die before they reach their first birthday.
Click here to see life expectancy in some African countries
In sub-Saharan African countries like Botswana and Malawi, the average life expectancy is already below 40 years, according to UNaids.
Security risk
Mr Agubuzu said women and children were the most vulnerable group, and their needs must be addressed.
He said diseases such as Aids, tuberculosis and related infectious diseases had become a risk to security and a major threat to development.
"Africa is distinctly characterised by abject socioeconomic conditions and unprecedented extreme demographic trends with far-reaching consequences," he said.
The UN estimates about $5bn is needed annually to help fight the spread of Aids in Africa and has called for more money from the international community.
Money
Just last week, the World Bank announced it had approved a second interest-free loan of $500m this year for African Aids initiatives.
World Bank President James Wolfensohn, who met African leaders a year ago, said intensifying the fight against HIV and Aids was central to the Bank's mission.
The World Bank and the United Nations agency UNAids estimate that approximately $3bn is needed every year to fund basic prevention, care and treatment programmes in Africa.
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